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Contact Info

William H. Sanders
Department Head
ECE ILLINOIS
306 N. Wright Street
Urbana, IL 61801
Ph: (217) 333-2300
Fax: (217) 244-7075
whs@illinois.edu

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Articles about Brian T. Cunningham

Brian T. Cunningham

Electrical and Computer Engineering
Brian T. Cunningham
Brian T. Cunningham
Professor
2000 Micro and Nanotechnology Lab
208 N. Wright Street
Urbana Illinois 61801
(217) 265-6291

Primary Research Area

  • Biomedical Imaging, Bioengineering, and Acoustics

Education

  • Ph.D. Electrical and Computer Engineering University of Illinois at Urbana-Champaign 1990
  • M.S. Electrical and Computer Engineering University of Illinois at Urbana-Champaign 1987
  • B.S. Electrical and Computer Engineering University of Illinois at Urbana-Champaign 1986

For more information

Research Statement

My research group is focused on the application of sub-wavelength optical phenomena and fabrication methods to the development of novel devices and instrumentation for the life sciences. The group is highly interdisciplinary, with expertise in the areas of microfabrication, nanotechnology, computer simulation, instrumentation, molecular biology, and cell biology. In particular, we are working on biosensors based upon photonic crystal concepts that can either be built from low-cost flexible plastic materials, or integrated with semiconductor-based active devices, such as light sources and photodetectors, for high performance integrated detection systems.

Using a combination of micrometer-scale and nanometer-scale fabrication tools, we are devising novel methods and materials for producing electro-optic devices with nanometer-scale features that can be scaled for low-cost manufacturing. Many of our techniques are geared for compatibility with flexible plastic materials, leading to applications such as low cost disposable sensors, wearable sensors, flexible electronics, and flexible displays. Because our structures manipulate light at a scale that is smaller than an optical wavelength, we rely on computer simulation tools such as Rigorous Coupled Wave Analysis (RCWA) and Finite Difference Time Doman (FDTD) to model, design, and understand optical phenomena within photonic crystals and related devices.

In addition to fabricating devices, our group is also focused on the design, prototyping, and testing of biosensor instrumentation for high sensitivity, portability, and resolution. Advanced instruments enable high resolution imaging of biochemical and cellular interactions with the ability to monitor images of biochemical interactions as a function of time. Using the sensors and instrumentation, we are exploring new applications for optical biosensor technology including protein microarrays, biosensor/mass spectrometry systems, and microfluidics-based assays using nanoliter quantities of reagents. The methods and systems developed in the laboratory are applied in the fields of life science research, drug discovery, diagnostic testing, and environmental monitoring.

Research Interests

  • Sensor design and instrumentation
  • Finite Difference Time Domain Analysis
  • Nanofabrication
  • Photonic Crystals
  • Optical Biosensors

Research Areas

Chapters in Books

  • "Photonic Crystals for Biosensing" by B.T. Cunningham, I.D. Block, L. Chan, N. Ganesh, M. Lu, and P.C. Mathias, in Selected Topics in Photonic Crystals and Metamaterials, Antonello Andreone, Andrea Cusano, Antonello Cutolo, and Vincenz, Editors, published by World Scientific, 2011.
  • "Design and implementation of vertically emitting distributed feedback lasers for biological sensing," M. Lu, S.S. Choi, C.J. Wagner, J.G. Eden, and B.T. Cunningham, in Label-Free Technologies for Drug Discovery, Edited by Matthew Cooper and Lorenz M. Mayr, published by Wiley, 2011.
  • "Label-Free Optical Biosensors: An Introduction," B.T. Cunningham, Label Free Biosensors - Techniques and Applications, edited by M. Cooper, Cambridge University Press, 2008.
  • "High Resolution Label-Free Detection Applied to Microarray Research," L. Laing and B.T. Cunningham, Functional Protein Microarray in Drug Discovery, edited by P.F. Predki, CRC Press, p. 217-236, 2007.
  • "Optical Biosensors," B.T. Cunningham, Encyclopedia of Sensors, American Scientific Publishers, 2005

Selected Articles in Journals

  • "Sculpting narrowband Fano resonances inherent in the large-area mid-infrared photonic crystal microresonators for spectroscopic imaging," J.-N. Liu, M.V. Schulmerich, R. Bhargava, and B.T. Cunningham, Optics Express, Vol. 22, No. 15, p. 18142-18158, 2014.
  • "Smartphone instrument for portable enzyme linked immunosorbent assays," K.D. Long, H. Yu, and B.T. Cunningham, Biomedical Optics Express, Vol. 5, No. 11, p. 3792-3806, 2014.
  • “Nanofluidic channels of arbitrary shapes fabricated by tip-based nanofabrication" H. Hu, Y. Zhuo, M. Oruc, B.T. Cunningham, W. King, Nanotechnology, Accepted, September 2014.
  • "Enhanced live cell imaging via photonic crystal enhanced fluorescence microscopy," W. Chen, K.D. Long, H. Yu, Y. Tan, J.S. Choi, B.A. Harley, and B.T. Cunningham, Analyst, Vol. 139, No. 22, p. 5955-5964, 2014.
  • "Smartphone fluorescence spectroscopy," H. Yu, Y. Tan, and B.T. Cunningham, Analytical Chemistry, Vol. 86, No. 17, p. 8805-8813, 2014.
  • "Plasmonic external cavity laser refractometric sensor," M. Zhang, M. Lu, C. Ge, and B. T. Cunningham, Optics Express, Accepted, August 2014.
  • "Detection of protein–small molecule binding using a self-referencing external cavity laser biosensor," M. Zhang, J. Peh, P. J. Hergenrother, and B. T. Cunningham, Journal of the American Chemical Society, vol. 136, pp. 5840-5843, 2014.
  • "Recognition of apoptotic cells by viable cells Is specific, ubiquitous, and species-independent: analysis using photonic crystal biosensors," G. Pattabiraman, E.A. Lidstone, B.T. Cunningham, D. Ucker, Molecular Biology of the Cell, Vol. 11, p. 1704-1714, 2014.
  • "Point-of-care detection and real-time monitoring of intravenously delivered drugs via tubing with an integrated SERS sensor," H.-Y. Wu, C.J. Choi, and B.T. Cunningham, Nanoscale, Vol. 6, No. 10., p, 5162-5171, 2014.
  • "Single nano particle detection using photonic crystal enhanced microscopy," Y. Zhuo, H. Hu, W. Chen, M. Lu, L. Tian, H. Yu, K.D. Long, E. Chow, W.P. King, S. Singamaneni, and B.T. Cunningham, Analyst, Vol. 139, No. 5, p. 1007-1015, 2014.
  • "Nanostructured optical photonic crystal biosensor for HIV viral load measurement," H. Shafiee, E. Lidstone, M. Jahangir, F. Inci, D. Kuritzkes, B.T. Cunningham, and U. Demirci, Nature Scientific Reports, Vol. 4, Article 4116, doi:10.1038/srep04116, 2014.
  • "A photonic crystal biosensor assay for ferritin utilizing iron-oxide nano particles," R.D. Peterson, B.T. Cunningham, and J. Andrade, Biosensors and Bioelectronics, Vol. 56, p. 320-327, 2014.
  • "Photonic crystal enhancement of a homogeneous fluorescent assay using submicron fluid channels fabricated by E-jet patterning," Y. Tan, E. Sutanto, A.G. Alleyne, and B.T. Cunningham, Journal of Biophotonics, Vol. 3-4, p. 266-275, 2014.
  • "Electrohydrodynamic jet printing of micro-optical devices," E. Sutanto, S. Onses, Y. Tan, B.T. Cunningham, and A. Alleyne, Manufacturing Letters, Vol. 2, No. 1, p. 4-7, 2014.
  • "Large infrared absorptance of bimaterial microcantilevers based on silicon high contrast grating," B. Kwon, M. Seong, J.-N. Liu, M.R. Rosenberger, M.V. Schulmerich, R. Bhargava, B.T. Cunningham, and W.P. King, Journal of Applied Physics, Vol. 114, p. 153511, 2013. DOI: 10.1063/1.4825313
  • "Photonic crystal enhanced microscopy for imaging of live cell adhesion," W. Chen, K.D. Long, M. Lu, V. Chaudhery, H. Yu, J.S. Choi, J. Polans, Y. Zhuo, B.A. Harley, and B.T. Cunningham, Analyst, Vol. 138, No. 20, p. 5886-5894, 2013.
  • "Sensitive detection of protein and miRNA cancer biomarkers using silicon-based photonic crystals and a resonance coupling laser scanning platform," S. George, V. Chaudhery, Y. Tan, M. Lu, and B.T. Cunningham, Lab on a Chip, Vol 13, p. 4053-4064, 2013 PMID: 23963502.
  • "Enhanced fluorescence emission using a photonic crystal coupled to an optical cavity," A. Pokhriyal, M. Lu, V. Chaudhery, S. George, and B.T. Cunningham, Applied Physics Letters,Vol. 102, pp. 221114-221116, 2013. PMCID: PMC3689753
  • "Label-Free Biodetection using a Smartphone," D. Gallegos, K. Long, H. Yu, P. Clark, Y. Lin, , S. George, P. Nath, and B.T. Cunningham, Lab on a Chip,Vol. 13, p. 2124-2132, 2013. DOI: 10.1039/C3LC40991K.
  • “Distributed Feedback Laser Biosensor Noise Reduction,” Y. Tan, A. Chu, M.Lu and B.T. Cunningham, IEEE Sensors Journal, Vol. 13, No. 5, p. 1972-1978, 2013.
  • "A self-referencing biosensor based upon a dual-mode external cavity laser," M. Zhang, C. Ge, M. Lu, Z. Zhang, and B.T. Cunningham, Applied Physics Letters, Vol. 201, p. 213701-213703, 2013. (Featured on Cover) PMCID: PMC3683028
  • "Nanostructured surfaces and detection instrumentation for photonic crystal enhanced fluorescence (invited review)," V. Chaudhery, S. George, M. Lu, A. Pokhriyal, and B.T. Cunningham, Sensors Journal, Vol. 13, p. 5561-5584, 2013. DOI: 10.3390/s130505561
  • “External cavity laser biosensor,” C. Ge, M. Lu, S. George, C. Wagner, J. Zheng, A. Pokhriyal, C. Siu, J.G. Eden, P.J. Hergenrother and B.T. Cunningham, Lab on a Chip, Vol. 13, No. 7, p. 1247-1256, 2013 (Featured on Front Cover).
  • "Colorimetric plasmon resonance imaging using nano Lycurgus cup arrays", M.R. Gartia, A. Hsiao, A. Pokhriyal, S. Seo, G. Kulsharova, B.T. Cunningham, T.C. Bond, and G.L. Liu, Advanced Optical Materials, Vol. 1, No. 1, p. 68-76, 2013. (Featured on Cover)
  • “Coupled external cavity photonic crystal enhanced fluorescence,” A. Pokhriyal, M. Lu, C. Ge and B.T. Cunningham, Journal of Biophotonics,Vol. 7, No. 5, p. 332-340, 2012. DOI: 10.1002/jbio.201200173 (Featured on Front Cover)
  • "Bidirectional scatter measurements of a guided mode resonant filter photonic crystal structure," M.A. Marciniak, S.R. Sellers, R B. Lamott, and B T. Cunningham, Optics Express, Vol. 20, No. 25, pp. 27242–27252, 2012.
  • "Plasmonic nanogap-enhanced Raman scattering using a resonant nanodome array," H.-Y. Wu, C. J. Choi and B.T. Cunningham, Small, Vol. 8, No. 18, p. 2769, 2012.
  • "Tunable ring laser with internal injection seeding and an optically-driven photonic crystal reflector," J. Zheng, C. Ge, C.J. Wagner, M. Lu, B.T. Cunningham, J.D Hewitt, and J.G. Eden, Optics Express, Vol. 20, No. 13, p. 14292-14301, 2012.
  • "A line-scanning detection instrument for photonics crystal enhanced fluorescence," V. Chaudhery, M. Lu, C.-S. Huang, J. Polans, R. Tan, R.C. Zangar, and B.T. Cunningham, Optics Letters, Vol. 37, No. 13, p. 2565-256, 2012.
  • "Photonic crystal enhanced fluorescence for early breast cancer biomarker detection," B.T. Cunningham and R.C. Zangar, Journal of Biophotonics, Vol. 8-9, p. 617-628, 2012. (Invited Review, Special Issue - Lab-on-a-Chip Diagnostics, featured on cover) PMC3844005.
  • "Multiplexed cancer biomarker detection using quartz-based photonic crystal surfaces," C.-S. Huang, V. Chaudhery, A. Pokhriyal, S. George, J. Polans, M. Lu, R. Tan, R.C. Zangar, B.T. Cunningham, Analytical Chemistry, Vol. 84, No. 2, p. 1126-1133, 2012. PMCID: PMC3264776.
  • "Nanoreplicated positive and inverted submicron polymer pyramids array for surface-enhanced Raman spectroscopy," Z. Xu, H.-Y. Wu, S.U. Ali, J. Jiang, B.T. Cunningham, and G.L. Liu, Journal of Nanophotonics, Vol. 5, p. 053526, 2011. (doi: 10.1117/1.3663259)
  • "Optimally designed narrowband guided-mode resonance reflectance filters for mid-infrared spectroscopy," J.-N. Liu, M.V. Schulmerich, R. Bhargava, and B.T. Cunningham, Optics Express, Vol. 19, No. 24, pp. 24182-24197, 2011.
  • "Spectral characteristics of single and coupled microresonator lasers comprising a replica-molded Bragg grating and dye-doped polymer," J. Zheng, M. Lu, C.J. Wagner, B.T. Cunningham, and J.G. Eden , Journal of the Optical Society of America B, Vol. 29, No. 2, p. 209-214, 2012.
  • "Biochemical Sensor Tubing for Point-of-Care Monitoring of Intravenous Drugs and Metabolites," C.J. Choi, J. Weyhenmayer, H.-Y. Wu, and B.T. Cunningham, Lab on a Chip, Vol. 12, No. 3, p. 574-581, 2012.
  • "Spatially selective photonic crystal enhanced fluorescence and application to background reduction for biomolecule detection assays," V. Chaudhery, M. Lu, C.-S. Huang, A. Pokhriyal, J. Polans, S.C. Schulz and B.T. Cunningham, Optics Express, Vol. 19, No. 23, p. 23327-23340, 2011.
  • "Angle-scanning photonic crystal enhanced fluorescence microscopy," V. Chaudhery, M. Lu, A. Pokhriyal, S. Schulz, and B.T. Cunningham, IEEE Sensors Journal, Vol. 12, No. 5, p. 1272-1279, 2012.
  • "Plastic-based distributed feedback laser biosensors in microplate format," Y. Tan, A. Chou, C. Ge, M. Lu, W. Goldshlag, J. Huang, A. Pokhriyal, S. George, and B.T. Cunningham, IEEE Sensors Journal, Vol. 12, No. 5, p. 1174-1180, 2012.
  • "Label-free imaging of cell attachment with photonic crystal enhanced microscopy," E.A. Lidstone, V. Chaudhery, A. Kohl, V. Chan, T.W. Jensen, L.B. Schook, R. Bashir, and B.T. Cunningham, Analyst, Vol. 136, No. 18, p. 3608-3615, 2011. DOI: 10.1039/C1AN15171A (Featured on the Cover)
  • "Quick Detection of Contaminants Leaching from Polypropylene Centrifuge Tube with Surface Enhanced Raman Spectroscopy and Ultra Violet Absorption Spectroscopy," Z. Xu, C.J. Choi, B.T. Cunningham, and G.L. Liu, Journal of Raman Spectroscopy, Vol. 42, No. 11, p. 1939-1944, 2011. DOI:10.1002/jrs.2950.
  • "Enhancement of pump efficiency of a visible wavelength organic distributed feedback laser by resonant optical pumping," C. Ge, M. Lu, Y. Tan, and B.T. Cunningham, Optics Express, Vol. 19, No. 6, p. 5086-5092, 2011.
  • "Enhanced quantum dot optical downconversion using asymmetric 2D photonic crystals," F. Yang and B.T. Cunningham, Optics Express, Vol. 19, No. 5, p. 3908-3918, 2011.
  • "A study on the cytotoxicity effects of amoora rohituka and chittagonga on breast and pancreatic cancer cells," L. Chan, S. George, I. Ahmad, S. Gosangari, A. Abbasi, B.T. Cunningham and K. Watkin, Evidence-Based Complementary and Alternative Medicine, Vol. 2011, Article ID 860605, 2011. DOI 10.1155/2011/860605
  • "Plasmonic coupling of SiO2-Ag "post-cap" nanostructures and silver film for surface enhanced Raman scattering," H.-Y. Wu and B.T. Cunningham, Applied Physics Letters, Vol. 98, No. 15, p. 3555342-3555344, 2011.
  • "Application of photonic crystal enhanced fluorescence to cancer biomarker microarrays," C.-S. Huang, S. George, M. Lu, V. Chaudhery, R. Tan, R.C. Zangar, and B.T. Cunningham, Analytical Chemistry, Vol. 83, No. 4, p. 1425-1430, 2011 (Featured on Cover).
  • "Label-free cell-based assays using photonic crystal optical biosensors," Analyst, Vol. 136, No. 6, p. 1090-1102, 2011. (Invited review) Published online February 3, 2011, DOI: 10.1039/C0AN00899K.
  • "Photonic crystal enhanced fluorescence using a quartz substrate to reduce limits of detection," A. Pokhriyal, M. Lu, V. Chaudhery, C.-S. Huang, S. Schulz, and B.T. Cunningham, Optics Express, Vol. 18, No. 24, p. 24793-24808, 2010.
  • "Photobleaching on photonic crystal enhanced fluorescence surfaces," V. Chaudhery, M. Lu, C. S. Huang, S. George, and B. T. Cunningham, Journal of Fluorescence, Vol. 21, No. 2, p. 707-714, 2011. DOI 10.1007/s10895-010-0760-8.
  • "Label-free prehybridization DNA microarray imaging using photonic crystals for quantitative spot quality analysis," S. George, I.D. Block, S.I. Jones, P.C. Mathias, V. Chaudhery, H.-Y Wu, P.Vuttipittayamongkol, L. Vodkin, and B.T. Cunningham, Analytical Chemistry, Vol. 82, No. 20, p. 8551-8557, 2010.
  • "Surface-enhanced Raman Nanodomes," C.J. Choi, A. Xu, H.-Y. Wu, L. Liu, and B.T. Cunningham, Nanotechnology, Vol 21, p. 415301 (2010) DOI: 10.1088/0957-4484/21/41/415301.
  • "Cytotoxicity Screening of Bangladeshi Medicinal Plant Extracts on Pancreatic Cancer Cells," S. George, S.V. Bhalerao, E.A.Lidstone, I.S. Ahmad, A. Abbasi, B.T. Cunningham, K.L. Watkin, BMC Complementary and Alternative Medicine, 10:52, 2010.
  • "Multi-color fluorescence enhancement from a photonic crystal surface," A. Pokhriyal, M. Lu, C. Huang, S.C. Schulz, and B.T. Cunningham, Applied Physics Letters, Vol. 97, No. 12, p. 121108-121110, 2010. PMCID: PMC2955725
  • "Improved Detection of Differentially Expressed Genes on a DNA Microarray by Photonic Crystal Enhanced Fluorescence," P.C. Mathias, S. I. Jones, H.-Y. Wu, F. Yang, D.O. Gonzalez, L.O. Vodkin, and B.T. Cunningham, Analytical Chemistry, Vol. 82, No. 16, p. 6854-6861, 2010.
  • "Comparison of label-free biosensing in microplate, microfluidic, and spot-based affinity capture assays," C.J. Choi, A.R. Belobraydich, L.L. Chan, P.C. Mathias, and B.T. Cunningham, Analytical Biochemistry, Vol. 405, No. 1, p. 1-10, 2010.
  • "Large-area organic distributed feedback laser fabricated by nanoreplica molding and horizontal dipping," C. Ge, M. Lu, X. Jian, Y. Tan, and B.T. Cunningham, Optics Express, Vol. 18, No. 12, p. 12980-12991, 2010.
  • "Integrated 2D photonic crystal stack filter fabricated using nanoreplica molding," F. Yang, G. Yen, and B.T. Cunningham, Optics Express, Vol. 18, No. 11, p. 11846-11858, 2010.
  • "Sensing micrometer-scale deformations vias stretching of a photonic crystal," N.L. Privorotskaya, C.J. Choi, B.T. Cunningham, and W.P. King, Sensors and Actuators A, Vol. 161, p. 66-71, 2010.
  • "Narrowband mid-infrared reflectance filters using guided mode resonance," A.K. Kodali, M. Schulmerich, J. Ip, G. Yen, B.T. Cunningham, and R. Bhargava, Analytical Chemistry, Vol. 82, p. 5697-5706, 2010.
  • "Distributed feedback laser biosensor incorporating a titanium dioxide nanorod surface," C. Ge, M. Lu, W. Zhang, and B.T. Cunningham, Applied Physics Letters,Vol. 96, p. 163702-163704, 2010 (DOI: 10.1063/1.3394259).
  • "Deposited nanorod films for biosensor applications," W. Zhang, S.-M. Kim, N. Ganesh, I.D. Block, P.C. Mathias, and B.T. Cunningham, Journal of Vacuum Science and Technology A, Vol. 28, No. 4, p. 996-1001, 2010.
  • "Coupling discrete metal nanoparticles to photonic crystal surface resonant modes and application to Raman spectroscopy," S.-m. Kim, W. Zhang, and B.T. Cunningham, Optics Express, Vol. 18, No. 5, p. 4300-4309, 2010.
  • " Magnification of photonic crystal fluorescence enhancement via TM resonance excitation and TE resonance extraction on a dielectric nanorod surface," H.-Y Yu, W. Zhang, P.C. Mathias, and B.T. Cunningham, Nanotechnology, Vol. 21, p. 125203-125210, 2010.
  • "Detection of growth factor binding to gelatin and heparin using a photonic crystal biosensor," L.L. Chan, A. Morgan, A. Sendemir-Urkmez, R. Jamison, and B.T. Cunningham, Materials Science and Engineering C, Vol. 30, p. 686-690, 2010.
  • "Identifying modulators of protein-protein interactions using photonic crystal biosensors," J.T. Heeres, S.-H. Kim, B.J. Leslie, E.A. Lidstone, B.T. Cunningham, and P.J. Hergenrother, Journal of the American Chemical Society, Vol. 131, No. 51, p. 18202-18203, 2009.
  • "Label-free detection of soybean rust spores using photonic crystal biosensor," R. Vittal, W. Zhang, L.L. Chan, B.T. Cunningham, and G. Hartman, Phytopathology Vol. 99, No. 6, S136, 2009.
  • "Photonic Crystal Surfaces as a General Purpose Platform for Label-Free and Fluorescent Assays," B.T. Cunningham, Journal of the Association of Laboratory Automation, Vol. 15, p. 120-135, 2010 (invited) DOI information: 10.1016/j.jala.2009.10.009, PMCID: PMC2850210.
  • "Optimizing the spatial resolution of photonic crystal label-free imaging," I.D. Block and B.T. Cunningham, Applied Optics, Vol. 48, No. 34, p.6567-6574, 2009.
  • "Vapor phase deposition of monofunctional alkoxysilanes for sub-nanometer level biointerfacing on oxide surfaces," B. Dorvel, R. Reddy, Jr., I.D. Block, P.C. Mathias, S.E. Clare, D.E. Bergstrom, B.T. Cunningham, and R. Bashir, Advanced Functional Materials, Vol. 20, p. 87-95, 2010, (DOI: 10.1002/adfm.200901688).
  • "Photonic Crystal Integrated Microfluidic Chip for Determination of Kinetic Reaction Rate Constants," C. J. Choi, I.D. Block, B. Bole, D. Dralle, B.T. Cunningham, IEEE Sensors Journal, Vol. 9, No. 12, p. 1697-1704, 2009.
  • "A detection instrument for enhanced fluorescence and label-free imaging on photonic crystal surfaces," I.D. Block, P.C. Mathias, N. Ganesh, I.D. Jones, B.R. Dorvel, V. Chaudhery, L. Vodkin, R. Bashir, and B.T. Cunningham, Optics Express, Vol. 17 Issue 15, pp.13222-13235, 2009.
  • "A method for identifying small molecule aggregators using photonic crystal biosensor microplates," L.L. Chan, E.A. Lidstone, K.E. Finch, J.T. Heeres, P.J. Hergenrother, and B.T. Cunningham, Journal of the Association for Laboratory Automation (JALA), Vol. 14, No. 6, p. 348-359, 2009. PMCID: PMC2950101
  • "Employing two distinct guided-mode resonances to improve fluorescence enhancement from photonic crystals," P.C. Mathias, H.-Y. Wu, and B.T. Cunningham, Applied Physics Letters, Vol. 95, p. 021111-021113, 2009.
  • "Cartilage tissue engineering on fibrous chitosan scaffolds produced by a replica molding technique," G. Ragetly, G. Slavik, B.T. Cunningham, D.J. Schaeffer, and D. Griffon, Journal of Biomedical Material Research Part A, Vol. 93, p. 46-55, 2010.
  • "Microfluidic chip for combinatorial mixing and screening of assays," B.R. Schudel, C.J. Choi, B.T. Cunningham, and P.J.A. Kenis, Lab on a Chip, Vol. 12, p. 1676-1680, 2009.
  • "Leaky-mode assisted fluorescence extraction: Application to fluorescence enhancement biosensors," N. Ganesh, I.D. Block, P.C. Mathias, W. Zhang, E. Chow, V. Malyarchuk, and B.T. Cunningham, Optics Express, Vol. 16, No. 26, p. 21626-21640, 2008.
  • "Application of Photonic Crystal Enhanced Fluorescence to a Cytokine Immunoassay," P.C. Mathias, N. Ganesh, and B.T. Cunningham, Analytical Chemistry, Vol. 80, No. 23, p. 9013-9020, 2008.
  • "Photonic crystals with SiO2-Ag "post-cap" nanostructure coatings for surface enhanced Raman spectroscopy," S.-M. Kim, W. Zhang, and B.T. Cunningham, Applied Physics Letters, Vol. 93, p. 143112, DOI: 10.1063/1.2998695, Published Online October 9, 2008.
  • "Rapid label-free selective detection of porcine rotavirus using photonic crystal biosensors," M.F. Pineda, L.L. Chan, T. Kuhlenschmidt, M. Kuhlenschmidt, and B.T. Cunningham, IEEE Sensors Journal, Vol. 9, No. 4, p. 470-477, 2009.
  • "Fluorescence enhancement by a photonic crystal with a nanorod-structured high index layer," W. Zhang and B.T. Cunningham, Applied Physics Letters, Vol. 93, p. 133115-133117, DOI: 10.1063/1.2994696, published online October 2, 2008.
  • "Plastic distributed feedback laser biosensor," M. Lu, S. S. Choi, U. Irfan, and B.T. Cunningham, Applied Physics Letters, Vol. 93, No. 11, p. 111113 (DOI 10.1063/1.2987484), Published Online September 18, 2008.
  • "Enhanced fluorescence on a photonic crystal surface incorporating nanorod structures," W. Zhang, N. Ganesh, P.C. Mathias, and B.T. Cunningham, Small, Vol. 4, No. 12, p. 2199-2203, 2008.
  • "General Method for Discovering Inhibitors of Protein-DNA Interactions using Photonic Crystal Biosensors," L.L. Chan, M.F. Pineda, J. Heeres, P. Hergenrother, and B T. Cunningham, ACS Chemical Biology, Vol. 3, No. 7, p. 437-448, 2008.
  • "VCSEL Optoelectronic Biosensor for Detection of Infectious Diseases," M.C.Y. Huang, C.F.R. Mateus, J.E. Foley, R. Beatty, B.T. Cunningham, and C.J. Chang-Hasnain, IEEE Photonics Technology Letters, Vol. 20, No. 6, p. 443-445, 2008.
  • "Advantages and application of label-free detection assays in drug screening," B.T. Cunningham and L.G. Laing, Expert Opinions in Drug Discovery, Vol. 3, No. 8, p. 891-901, 2008.
  • "Label free biosensor incorporating a replica-molded, vertically emitting distributed feedback laser," M. Lu, S. S. Choi, C. J. Wagner, J. G. Eden, and B. T. Cunningham, Applied Physics Letters, Vol. 92, 261502, 2008.
  • "Honey I Shrunk the World: Research and Development in Nanotechnology at the University of Illinois," I.S. Ahmad and B.T. Cunningham, IEEE Nanotechnology Magazine, December, p. 5-10, 2008.
  • "Low temperature plasma channels generated in microcavity trenches with widths 20-150 um and aspect rations as large as 10000:1", M. Lu, S.-J. Park, B.T. Cunningham, and J.G. Eden, Applied Physics Letters, Vol. 92, p. 101928, 2008.
  • "Distance dependence of fluorescence enhancement from photonic crystal surfaces," N. Ganesh, P.C. Mathias, W. Zhang, and B.T. Cunningham, Journal of Applied Physics, Vol. 103, p. 083104, 2008.
  • "High Sensitivity Plastic-Substrate Photonic Crystal Biosensor," I.D. Block, M.F. Pineda, C.J. Choi, and B.T. Cunningham, IEEE Sensors Journal, Vol. 8, No. 9, p. 1546-1547, 2008.
  • "Optically tuned resonant optical reflectance filter," F. Yang, G. Yen, G. Rasigade, J. Soares, and B.T. Cunningham, Applied Physics Letters, Vol. 92, No. 9, p. 091115, DOI: 10.1063/1.289071, 2008.
  • "Graded Wavelength One-Dimensional Photonic Crystal Reveals Spectral Characteristics of Enhanced Fluorescence," P.C. Mathias, N.Ganesh, W.Zhang, and B.T. Cunningham, Journal of Applied Physics, Vol. 103, p. 094320, 2008.
  • "Vertically emitting, dye-doped polymer laser in the green (lambda ~ 536 nm) with a second order distributed feedback grating fabricated by replica molding," M. Lu, J.G. Eden, and B.T. Cunningham, Optics Communications, Vol. 281, p. 3159-3162, 2008.
  • "High Sensitivity Photonic Crystal Biosensor Incorporating Nanorod Structures for Enhanced Surface Area," W. Zhang, N. Ganesh, I.D. Block and B.T. Cunningham, Sensors and Actuators B, Vol. 131, p. 279-284, 2008.
  • "A sensitivity model for predicting photonic crystal biosensor performance," I.D. Block, N. Ganesh, M. Lu, and B.T. Cunningham, IEEE Sensors, Vol. 8, No. 3, p. 274-280, 2008.
  • "Label-free imaging of cancer cells using photonic crystal biosensors and application to cytotoxicity screening of a natural compound library," L.L. Chan, S. Gosangari, K.L. Watkin, and B.T. Cunningham, Sensors and Actuators B, Vol. 132, p. 418-425, 2008.
  • "A Replica Molding Technique for Producing Fibrous Chitosan Scaffolds for Cartilage Engineering," G.J. Slavik, G. Ragetly, N. Ganesh,a D.J. Griffon, and B.T. Cunningham, Journal of Materials Chemistry, Vol. 17, p. 4095 - 4101, 2007.
  • "A voltage-tuned resonant reflectance optical filter for visible wavelengths fabricated by nanoreplica molding," F. Yang, G. Yen, and B.T. Cunningham, Applied Physics Letters, Vol. 90, p. 261109-261111, 2007.
  • "Enhanced fluorescence emission from quantum dots on a photonic crystal surface," N. Ganesh, W. Zhang, P.C. Mathias and B.T. Cunningham, Nature Nanotechnology, v 2, no 8, p. 515-520, 2007 .
  • "A 96-well microplate incorporating a replica molded microfluidic network integrated with photonic crystal biosensors for high throughput kinetic biomolecular interaction analysis," C. J. . Choi and B.T. Cunningham, Lab On A Chip, Vol. 7, p. 550-556, 2007.
  • "Compact Wavelength Detection System Incorporating a Guided-Mode Resonance Filter," N.Ganesh, A. Xiang, N.B. Beltran, D.W. Dobbs, and B.T. Cunningham, Applied Physics Letters, v. 90, p. 081103-081106, 2007.
  • "Combined Enhanced Fluorescence and Label-Free Biomolecular Detection with a Photonic Crystal Surface," P.C. Mathias, N. Ganesh, L.L. Chan, and B.T. Cunningham, Applied Optics, Vol. 46, No. 12, p. 2351-2360, 2007.
  • "A label-free photonic crystal biosensor imaging method for detection of cancer cell cytotoxicity and proliferation," L. Chan, S. Gosangari, K. Watkin, and B.T. Cunningham, Apoptosis, Vol. 12, No, 6, p. 1061-1068, 2007.
  • "Microplasma devices and arrays fabricated by plastic-based replica molding," M. Lu, S.-J. Park, J.G. Eden, and B.T. Cunningham, JMEMS, Vol. 16, No. 6, p. 1397-1402, 2007.

Invited Lectures

  • "Photoinc crystals, biomarkers, and cells," IEEE EMBS Micro and Nanotechnology in Medicine Conference, Oahu, HI, December 2014.
  • "Microfluidic Integration of Photonic Crystal Enhanced Fluorescence Technology for High Sensitivity, Multiplexed Detection of Serum Biomarkers," NIH Innovative Molecular Analysis Technologies Program Annual Workshop, Bethesda, MD, November 2014.
  • "Chemical and Biological Detection for Diagnostic, Food Safety, and Drug Safety using the Internal Sensing Capabilities of Mobile Devices," Lester Wolfe Workshop at MIT, Cambridge, MA, November 2014.
  • 'Photonic crystal biosensors," IEEE Sensors Conference (Special Session on Photonic Crystal Biosensors), Valencia, Spain, November 2014.
  • "Four Orders of Magnitude: Nanophotonic Biosensors for Detection of Molecules to Tissues," Boston University Photonics Seminar, Boston, MA, October 2014.
  • "Smartphone Biosensors for Diagnostics, Food Safety, and Environmental Monitoring," SelectBio Point of Care Diagnostics World Congress, San Diego, CA, September 2014.
  • "Biosensors in Food Safety Applications," Department of Food Science and Human Nutrition, Graduate Seminar, University of Illinois at Urbana-Champaign, Champaign, IL, September 2014.
  • "Smartphone Biosensors for Diagnostics, Food Safety, and Environmental Monitoring," OSA Applied Industrial Optics Conference, Seattle, WA, July 2014.
  • "Four Orders of Magnitude: Nanophotonic Biosensors for Detection of Molecules to Tissues," Plenary Lecture, Asia-Pacific Conference of Transducers and Micro-Nano Technology (APCOT), Daegu, South Korea, June 2014.
  • "Laser Biosensors for Drug Discovery," 2014 Device Research Conference, Plenary Lecture, Santa Barbara, CA, June 2014.
  • "Optical Sensors in the Life Sciences," Tsinghua University-Illinois Nanotechnology Symposium, Urbana, IL, April 2014.
  • "Optical Sensors in Diagnostics and Life Science Research," Beckton Dickenson Technologies Division Seminar, Raleigh, NC, February 2014.
  • "Handheld Smartphone Biosensing," Molecular Medicine Tri-Conference on Point-of-Care Diagnostics, San Francisco, CA, February 2014.
  • "Photonic Crystal Enhanced Microscopy: A New Tool for Cell Imaging and Biomarker Detection," University of Houston, Department of Electrical and Computer Engineering Distinguished Speaker Series, Inaugural Lecture, Houston, TX, February 2014.
  • "Photonic Crystal Enhanced Microscopy: A New Tool for Cell Imaging and Biomarker Detection," Institute of Genomic Biology Seminar, Urbana, IL, January 2014.
  • "Friendly Photons: Optical Sensors in Life Science and Medicine," Keynote Lecture, International Conference on Sensing Technology, Wellington, New Zealand, December 2013.
  • "Friendly Photons: Optical Sensors in Life Science and Medicine," Berkeley Sensor and Actuator Center (BSAC) Seminar, University of California at Berkeley, Berkeley, CA, November 2013.
  • "Friendly Photons: Optical Sensors in Life Science and Medicine," Penn State University, Department of Engineering Science and Mechanics Seminar, State College, PA, October 2013.
  • "Nanostructures in Optics for Biomedicine," Washington University Mechanical Engineering and Material Science Department Seminar, St. Louis, MO, September 2013.
  • "Lighting the Way: Optical Sensors in the Life Sciences," IEEE SmartTech Workshop, Waltham, MA, September, 2013.
  • "The biosensor business," Technology Entrepreneurship Program, University of Illinois School of Management, Urbana, IL, September, 2013.
  • "Optical Sensors in Life Science and Medicine," Tutorial Presentation, IEEE Photonics Conference, Bellevue, WA, September, 2013.
  • "Optical Sensors in Drug Discovery," Keynote Presentation, 1st Mining the Microbial Genome Symposium, Institute for Genomic Biology, Urbana, IL, August, 2013.
  • "Biosensors in diagnostics, point-of-care monitoring, life science research, and pharmaceutical screening," Bionanotechnology Summer Institute, Urbana, IL, August 2013.
  • "Biosensors in diagnostics, point-of-care monitoring, life science research, and pharmaceutical screening," Austrian Institute of Technology Seminar, Vienna, Austria, July 2013.
  • "Friendly Photons: Optical Sensors in Life Science and Medicine," National Institute of Standards Technology, Bethesda, MD, June, 2013.
  • "Application of nanosensors for prevention of food contamination," Illinois Institute of Technology Institute of Food Safety and Health Seminar, Bedford Park, IL, January 2013.
  • "Smartphone biosensors for health, environmental monitoring, and food safety," NSF EFRI Program Topic Proposal, Arlington, VA, January 2013.
  • "Flexible optical nanosensors in disposable biomedical tubing," CMOS Emerging Technologies Conference, Vancouver, BC, July 2012.
  • "Subwavelength photonics for biosensing," OSA Integrated Photonics Research, Silicon and Nanophotonics Conference, Colorado Springs, CO, June 2012.
  • "Photonic Crystals: A versatile platform for optics-based biological detection," SPIE Photonics West, San Francisco, CA, January 2012.
  • "Getting molecules to see the light: Nanostructures and instruments for biomedical detection," W.M. Keck Lecture, University of California at Santa Cruz, September 2011.
  • "Getting molecules to see the light: Nanostructures and instruments for biomedical detection," Boston University Photonics Center Seminar, Boston MA, August 2011.
  • "Getting molecules to see the light: Nanostructures and instruments for biomedical detection," Draper Laboratory Seminar, Cambridge, MA, August 2011.
  • "Cell-based assays using photonic crystal biosensors," Conference on Lasers and Electro Optics (CLEO), Baltimore, MD, May 2011.
  • "Sensors for Biomedical Tubing," Nano Electronics-Photonics Seminar, University of Illinois at Urbana-Champaign, April 2011.
  • "Biosensing with Photonic Crystal Surfaces," University of California Davis, Center for Biophotonics Science and Technology (CBST) Seminar, March 2011.
  • "High resolution imaging of cell activity using photonic crystal surfaces," LEOS Winter Topical Meeting, Keystone, CO, January 2011.
  • "Nanophotonics in Biosensing," 1st International Symposium on Nanomedicine: Past, Present & Future Prospects, Karachi, Pakistan, December 2010.
  • "Biosensing with Photonic Crystal Surfaces," IEEE Photonics Society 2010 Annual Meeting, Denver, CO, November 2010.
  • "Label-free detection and fluorescence enhancement with photonic crystal surfaces," Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, October 2010
  • "Resonant excitation and enhanced extraction of quantum dots in plastic-based photonic crystals," BAE Systems Seminar, Merrimack, NH, September 2010.
  • "Sensors using photonic crystal surfaces," International Nano-Optoelectronics Workshop (iNOW), Beijing, China, August 2010.
  • "Fluorescence-based biodetection and fluorescence amplification," NSF Biosensing-Bioactuation Summer Institute 2010, Champaign, IL, July 2010.
  • "Application of biosensors in cancer research and diagnostics," Department of Medicine Seminar, University of Illinois Chicago, Chicago, IL, April 2010.
  • "Biosensors for Cell and Bacteria Surface Interaction Analysis," Department of Medicinal Chemistry Seminar, University of Illinois Chicago, Chicago, IL, March 2010.
  • "Deposited Nanorod Films for Biosensor Applications," iOptics Seminar, Urbana, IL, February 2010
  • "Label-Free Cell Assays Using Photonic Crystal Biosensors," Center for Cellular Mechanics Seminar, Urbana, IL, February 2010.
  • "Photonic crystal enhanced fluorescence," B.T. Cunningham, SPIE Photonics West, Special Session: Frontiers in Pathogen Detection: From Nanosensors to Systems, San Francisco, CA, January 2010. (Proc. SPIE Vol. 7553, p. 755302-1)
  • "Application of Photonic Crystal Enhanced Fluorescence to a Cytokine Immunoassay," B.T. Cunningham, EMBC 2009 Conference, Minneapolis, MN, September 2009.
  • "Screening Small Molecule and Cell-Based Targets using Photonic Crystal Biosensors," B.T. Cunningham, Target Discovery World Congress, San Francisco, CA, August 2009.
  • "Deposited nanorod films for biosensor applications," W. Zhang, S.-M. Kim, N. Ganesh, I. Block, P.C. Mathias, and B.T. Cunningham, AVS 56th International Symposium & Exhibition, San Jose, CA, November, 2009.
  • "A general method for screening protein-DNA interactions using photonic crystal biosensor microplates," ACHEMA Conference, Frankfurt, Germany, May 2009.
  • "Photonic Biosensors," Electrical Engineering Department Colloquium, University of Washington, Seattle, WA, May 2009.
  • "Microplate-based, Label-free Applications: Native Cell Profiling and Pharmaceutically Relevant Targets," Society for Biomolecular Screening Spring Meeting, Lille, France, April 2009.
  • "Nanophotonic resonators as biosensing substrates," Ecole Polytechnique de Montreal, Engineering Physics Department Seminar, March 2009.
  • "Photonic crystal biosensors for high throughput drug discovery, environmental monitoring, and biomarker detection," Pittcon 2009, Chicago, IL, March 2009.
  • "Photonic crystals: A platform for label-free and enhanced fluorescence biomolecular and cellular assays," 2008 MRS Fall Meeting, Boston, MA, December 2008.
  • "Optical Resonators for Label Free Detection: Photonic Crystals and Lasers," University of Illinois Electromagnetics Symposium, Urbana, IL, September, 2008.
  • "Photonic Crystal Biosensors and Tunable Resonant Optical Devices," IEEE LEOS Conference on Optical MEMS and Nanophotonics, Freiburg, Germany, August, 2008.
  • "Sensors for Embedded Intelligence," Baxter Corporation Biannual Conference on Global R&D, Vienna, Austria, July, 2008.
  • "Preliminary studies on biologically active proteins/peptides from medicinal plants," ASABE Conference, Providence, RI, June, 2008.
  • "Photonic crystal biosensors for label-free detection and fluorescence enhancement," Gordon Research Conference in Bioanalytical Sensors, Providence, RI, June, 2008.
  • "Tunable photonic crystal reflection filters on flexible plastic substrates," Tri-Service Information Exchange on Agile Laser Protection, Hilton Head, SC, April 2008.
  • "Photonic crystal optofluidics for high throughput biosensing," C.J. Choi, and B.T. Cunningham, Conference on Lasers and Electro Optics, May 2008, San Jose, CA.
  • "Optical Resonators for Label-Free Detection: Photonic Crystals, Microrings, and Lasers," SBS Symposium on Label-Free Technologies in Drug Discovery, June 2008, Dresden, Germany.
  • "Photonic Crystal Biosensors," SPIE Defense and Security Symposium, Orlando, FL, March 2008.

Patents

  • 8,864,542 Polymer microcavity and microchannel device and array fabrication method (J.E. Eden, S.-J. Park, M. Lu, and B.T. Cunningham), October 21, 2014.
  • 8,687,187 Surface enhanced Raman spectroscopy on optical resonator (e.g. photonic crystal) surfaces (B.T. Cunningham), April 1, 2014.
  • 8,593,630 Discrete frequency spectroscopy and instrumentation (R. Bhargava and B.T. Cunningham), November 26, 2013.
  • 8,580,578 Optical detection of label-free biomolecular interactions using micro replicated plastic (B.T. Cunningham, J. Pepper, B Lin, P. Li, H. Pien, J. Qiu), November 12, 2013.
  • 8,497,631 Polymer microcavity and microchannel devices and fabrication method (J.G. Eden, S.-J. Park, M. Lu, and B.T. Cunningham), July 30, 2013.
  • 8,384,892 Surface enhanced Raman spectroscopy on optical resonator (e.g., photonic crystal) surfaces (B.T. Cunningham), February 26, 2013.
  • 8,344,333 Multi-color fluorescence enhancement from a photonic crystal surface (M. Lu, B.T. Cunningham, A. Pokhriyal) January 1, 2013.
  • 8,298,780 Method of detection of changes in cells (R. Wagner, R. Fernandez, B.T. Cunningham, L. Laing) October 30, 2012.
  • 8,268.637 Label-free biosensors based upon distributed feedback laser (B.T. Cunningham and M. Lu) September 18, 2012.
  • 8,247,240 Method and apparatus for biosensor spectral shift detection (H. Pien, W.C. Karl, D. Puff, P. Li, and B.T. Cunningham) August 21, 2012.
  • 8,101,423 Label-free high-throughput optical technique for detecting bimolecular interactions (B.T. Cunningham, J. Pepper, B. Lin, P. Li) January 24, 2012.
  • 7,968,836 Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and uses thereof for biomolecular interaction analysis (B.T. Cunningham and C. Choi), June 28, 2011
  • 7,961,315 Fluorescence detection enhancement using photonic crystal extraction (B.T. Cunningham, N. Ganesh, P.C. Mathias, I.D. Block) June 14, 2011
  • 7,960,170 Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor (S.C. Schulz, B.T. Cunningham. L.G. Laing, P.Y. Li, B. Binder, G. Jogikalmath, A. Borsody, June 14, 2011.
  • 7,935,520 Optical detection of label-free biomolecular interactions using microreplicated sensor elements (B.T. Cunningham, J. Pepper, B. Lin, P. Li, H. Pien, and J. Qiu), May 3, 2011.
  • 7,927,789 Self-referencing biodetection method and patterned bioassays, (C. Baird, B.T. Cunningham, and P. Li), April 19, 2011.
  • 7,923,239 Guided mode resonant filter biosensor using a linear grating surface structure (B.T. Cunningham, P. Li, J. Qiu, and H. Pien), April 12, 2011.
  • 7,875,434 Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor, (B. Lin, B.T. Cunningham, P. Li), January 25, 2011.
  • 7,863,052 Grating-based sensor combinign label-free binding detection and fluorescence amplification and readout system for sensor, (S.C. Schulz, B.T. Cunningham, L.G. Laing, P.Y. Li, B. Binder, G. Jogikalmath, and A. Borsody), January 4, 2011.
  • 7,961,315 Fluorescence detection enhancement using photonic crystal extraction (B.T. Cunningham, N. Ganesh, P.C. Mathias, and I.D. Block) June 14, 2011.
  • 7,869,032 Biosensors with Porous Dielectric Surface for Fluorescence Enhancement and Methods of Manufacture, (W. Zhang and B.T. Cunningham) January 11, 2011.
  • 7.854,505 Passive and active photonic crystal structures and devices (B.T. Cunningham and D.W. Dobbs) December 21, 2010.
  • 7,790,406 Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor (B.T. Cunningham, P.Y. Li, L.G. Liang, G. Jogikalmath) September 7, 2010.
  • 7,768,640 Fluorescence detection enhancement using photonic crystal surfaces (B.T. Cunningham, N. Ganesh, P.C. Mathias, and I.D. Block) August 3, 2010.
  • 7,756,365 Near ultraviolet-wavelength photonic-crystal biosensor with enhanced surface to bulk sensitivity ratio (B.T. Cunningham, N. Ganesh, and I.D. Block) July 13, 2010.
  • 7,742,662 Photonic crystal sensors with integrated fluid containment structure, (B.T. Cunningham) June 22, 2010.
  • 7,737,392 Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and used thereof for biomolecular interaction analysis, (B.T. Cunningham and C.J. Choi), June 15, 2010
  • 7,718,440 Method and apparatus for biosensor spectral shift detection, (H. Pien, W.C. Karl, D. Puff, P. Li, and B.T. Cunningham), May 18, 2010
  • 7,622,027 Biosensor electrophoresis (B.T. Cunningham) November 24, 2009.
  • 7,615,339 Method for producing a colorimetric resonant reflection biosensor on rigid surfaces (B.T. Cunningham and J. Qiu), November 10, 2009.
  • 7,611,836 Method of making a plastic colorimetric resonant reflection biosensor on rigid surfaces (J. Qiu, P. Li, and B.T. Cunningham), November 3, 2009.
  • 7,575,939 Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements (B.T. Cunningham, J. Pepper, B. Lin, P. Li, H. Pien, and J. Qiu), August 18, 2009.
  • 7,534,578 Self-referencing biodetection method and patterned bioassays (C. Baird and B.T. Cunningham) May 19, 2009
  • 7,531,786 Photonic crystal sensors with integrated fluid containment structure (B.T. Cunningham and C.J. Choi) May 12, 2009.
  • 7,521,769 Photonic crystal biosensor and fabrication method (B.T. Cunningham) April 21, 2009.
  • 7,497,992 Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers (B.T. Cunningham, P.Y. Li, C. Chang-Hasnain, C. Mateus) March 3, 2009.
  • 7,479,404 Photonic crystal biosensor structure and fabrication method (B.T. Cunningham, I. Block, L. L-Y. Chan) January 20, 2009.
  • 7,468,138 Flexural plate wave sensor (M.S. Weinberg, B.T. Cunningham, and E. Hildebrant) December 23, 2008.
  • 7,422,891 Label-free high-throughput optical technique for detecting biomolecular interactions (B.T. Cunningham) September 9, 2008.
  • 7,371,562 Guided mode resonant filter biosensor using a linear grating surface structure (B.T. Cunningham, J. Pepper, B. Lin, P. Li, J. Qiu, H. Pien) May 13, 2008.
  • 7,327,454 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, F, DeFilippi) February 5, 2008.
  • 7,312,090 Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor (B. Lin, J. Pepper, B.T. Cunningham, J. Gerstenmaier, P. Li, J. Qiu, and H. Pien) December 25, 2007.
  • 7,309,614 Self-referencing biodetection method and patterned bioassays (C. Baird, B.T. Cunningham, P. Li) December 18, 2007.
  • 7,301,628 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, and F. DeFilippi) November 27, 2007.
  • 7,300,814 Method for fabricating micro-mechanical devices (B.T. Cunningham and M.S. Weinberg) November 27, 2007.
  • 7,300,803 Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor (B. Lin, J. Pepper, B.T. Cunningham, J. Gerstenmaier, P.Y, Li, J. Qiu, and H. Pien) November 27, 2007.
  • 7,298,477 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, and F. DeFilippi) November 20, 2007.
  • 7,292,336 Method and instrument for detecting biomolecular interactions (B.T. Cunningham and P.Y. Li) November 6, 2007.
  • 7,266,990 Flexural plate wave sensor and array (B.T. Cunningham and J.R. Williams), September 17, 2007.
  • 7,264,973 Label-free methods for performing assays using a colorimetric resonant optical biosensor (B. Lin, B.T. Cunningham, and P.Y. Li) September 4, 2007.
  • 7,217,574 Method and apparatus for biosensor spectral shift detection (H. Pien, W.C. Karl, D. Puff, P.Y. Li, and B.T. Cunningham) May 15, 2007.
  • 7,202,076 Label-free high-throughput optical technique for detecting biomolecular interactions (B.T. Cunningham, J. Pepper, B. Lin, P.Y. Li, and H. Pien) April 10, 2007.
  • 7,197,198 Biosensor substrate structure for reducing the effects of optical interference (S.C. Schulz and B.T. Cunningham) March 27, 2007.
  • 7,175,980 Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities (J. Qiu, P.Y. Li, and B.T. Cunningham) February 13, 2007.
  • 7,171,844 Apparatus and method for measuring the mass of a substance (B.T. Cunningham and J.R. Williams) February 6, 2007.
  • 7,170,599 Method and instrument for detecting biomolecular interactions (B.T. Cunningham and P.Y. Li) January 30, 2007.
  • 7,158,230 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, and F. DeFilippi) January 2, 2007.
  • 7,153,702 Label-free methods for performing assays using a colorimetric resonant reflection optical biosensor (B. Lin, J. Pepper, B.T. Cunningham, J. Gerstenmaier, P. Li, J. Qiu, and H. Pien) December 26, 2006.
  • 7,148,964 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, and F. DeFilippi) December 12, 2006.
  • 7,142,296 Method and apparatus for detecting biomolecular interactions (B.T. Cunningham, P.Y. Li, and F. DeFilippi) November 28, 2006.
  • 7,118,710 Label-free high-throughput optical technique for detecting biomolecular interactions (B. T. Cunningham) October 10, 2006.
  • 7,109,633 Flexural plate wave sensor (M.S. Weinberg, B.T. Cunningham, and E. Hildebrant) September 19, 2006.
  • 7,101,660 Method for producing a colorimetric resonant reflection biosensor on rigid surfaces (B.T. Cunningham and J. Qiu) September 5, 2006.
  • 7,094,595 Label-free high-throughput optical technique for detecting biomolecular interactions (B.T. Cunningham, J. Pepper, B. Lin, P. Li, and H. Pien) August 22, 2006.
  • 7,074,311 Biosensor electrophoresis (B.T. Cunningham) July 11, 2006.
  • 7,070,987 Guided mode resonant filter biosensor using a linear grating surface structure (B.T. Cunningham, J. Pepper, B. Lin, P. Li, J. Qiu, and H. Pien) July 4, 2006.
  • 7,023,544 Method and instrument for detecting biomolecular interactions (B.T. Cunningham and P. Li) April 4, 2006.
  • 7,000,453 Flexural plate wave sensor and array (B.T. Cunningham and J.R. Williams) February 21, 2006.
  • 6,990,259 Photonic crystal defect cavity biosensor (B.T. Cunningham) January 24, 2006.
  • 6,951,715 Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements (B.T. Cunningham, J. Pepper, B. Lin, P. Li, H. Pien, and J. Qiu) October 4, 2005.
  • 6,851,297 Flexural plate wave sensor and array (B.T. Cunningham and J.R. Williams) February 8, 2005.
  • 6,837,097 Flexural plate wave sensor and array (B.T. Cunningham and J.R. Williams) January 4, 2005.
  • 6,688,158 Flexural plate wave sensor and array (B.T. Cunningham and J.R. Williams) February 10, 2004.
  • 5,903,383 Electrostatic memory micromirror display system (J. Bernstein and B.T. Cunningham) May 11, 1999.
  • 6,168,906 Micromachined membrane with locally compliant and stiff regions and method of making same (B.T. Cunningham and J.J. Bernstein) January 2, 2001.
  • 5,900,630 Radiation detection apparatus (T.T. Tang, B.T. Cunningham, D.L. Lee, R.F. Adams, and S. Liberman) May 4, 1999.
  • 5,688,699 Microbolometer (B.T. Cunningham and B. Patel) November 18, 1997.
  • 5,399,897 Microstructure and method of making such structure (B.T. Cunningham and P.V. Richard), March 21, 1995

Honors

  • National Academy of Inventors, 2014
  • Fellow of the Optical Society of America, 2014
  • 2013 Massachusetts Excellence Award, SRU Biosystems, Small Business Institute for Excellence in Commerce
  • IEEE Sensors Council Distinguished Lecturer, 2013
  • Chairperson, NIH Study Section on Instrument and System Development, 2012-2014
  • Fellow of the American Institute for Medical and Biological Engineering (AIMBE), 2012
  • Fellow of IEEE, 2012
  • Medical Scholars Program Outstanding Advisor Award, 2010
  • Engineering Council Award for Excellence in Advising, 2010
  • Senior Member, IEEE, 2007
  • Army Research Fellowship, 1987-1990
  • Semiconductor Research Corporation Fellowship Award University of Illinois at Urbana-Champaign 1987
  • Bronze Tablet University of Illinois at Urbana-Champaign 1986

Teaching Honors

Incomplete list of faculty rated "excellent" by students, Fall 2005, Spring 2007, Spring 2008, Spring 2010, Spring 2011, Spring 2012, Spring 2013

Research Honors

  • 2014, IEEE Engineering in Medicine and Biology Society (EMBS) Technical Achievement Award
  • 2010 IEEE Sensors Council Technical Achievement Award "For the invention, development, and commercialization of sensors and detection instruments based on photonic crystals."
  • 2009 Association for Laboratory Automation Innovation Award Top Candidate for paper "A General Method for Screening Protein-DNA Interactions using Label-Free Photonic Crystal Biosensor Microplates" by L.L. Chan, M. Pineda, J. Heeres, P.J. Hergenrother, and B.T. Cunningham
  • 2008 Grainger Program in Emerging Technologies Grant for "Nanofilter-based Infrared Spectroscopic Imaging" (co-awarded with Prof. Rohit Bhargava)
  • 2008 Xerox Award for Faculty Research
  • 2007 3M Nontenured Faculty Grant
  • 2006 Draper Laboratory Best Patent Award, "Flexural Plate Wave Sensor and Array"
  • 1996 Draper Laboratory Engineering Lead Project: "MEMS Chemical Analysis Array"