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Michael Insana

Michael Insana
Michael Insana

Professor
Bioengineering
3120 Digital Computer Lab, MC-278
1304 W. Springfield
Urbana, Illinois 61801
(217) 244-0739
mfi@illinois.edu

Education

Ph.D. Medical Physics, University of Wisconsin, Madison 1983

Research Statement:

Laboratory research focuses on the development of novel ultrasonic instrumentation and methods for imaging soft tissue microstructure, viscoelasticity and blood flow. The goal is to understand basic mechanisms of cancerous lesion formation, metastatic progression, responses to therapy, and sources of image contrast. Research includes the fundamentals of imaging system design and performance evaluation, signal processing, detection and estimation. The lab uses polymer hydrogels to develop models of visco- and poroelastic behavior of soft tissues for cancer imaging. Insana’s lab also investigates spatio-temporal filtering for noise reduction and enhanced spatial resolution with applications in breast elasticity imaging and arterial-wall shear-stress estimation.

Teaching Statement:

Graduate course BIOE 504 "Analytic Methods for Bioengineering" is a core course taken by all bioengineering graduate students. The goal is to review mathematical and computation methods applied to biological systems design and evaluation. It includes linear systems, probability, random processes, differential equations, control systems, and data modeling.
Undergraduate course BIOE 205 "Circuits and Systems for Bioengineers" is an introduction to linear systems analysis applied to electrical, mechanical, and biological systems.

Research Interests:

  • Medical imaging systems development particularly for applications breast cancer, vascular disease, and kidney disease. Ultrasonics, signal processing, signal detection, elasticity imaging, soft tissue biomechanics, polymer mechanics, complex system modeling.

For more information:

Prof. Insana's Ultrasonic Imaging web page
Affiliate Faculty: Beckman Institute
Affiliate Faculty: Department of Electrical and Computer Engineering

Major Consulting Activities

  • NAtional Institutes of Health (Chair of ultrasonic imaging technology special study section), Bethesda MD

Professional Registrations

  • Biomedical Engineering Society, 2008 - present

Resident Instruction

  • BIOE 120 - Introduction to Bioengineering (UIUC) - 2008-2009
  • BIOE 205 - Circuits and Systems in Bioengineering (UIUC) - 2007 to present

Books Edited or Co-Edited (Original Editions)

  • M.F. Insana and S.A. Wickline (editors), Proceedings of the IEEE, Volume 96, No. 3, Special Issue: "Multimodality Biomolecular Imaging", March Issue 2008.

Articles in Journals

  • Coussot, C, Kalyanam, S, Yapp RD, Insana, MF, "Fractional derivative models for ultrasonic characterization of polymer and breast tissue viscoelasticity," IEEE Trans Ultrason Ferro Freq Contrl (in press) 2009.
  • Yapp RD, Insana MF, "pH-induced contrast in viscoelasticity imaging of biopolymers," Phys Med Biol 54:1089-1109, 2009.
  • Qiu Y, Sridhar M, Tsou JK, Lindfors KK, Insana MF, "Ultrasonic viscoelasticity imaging of nonpalpable breast tumors: preliminary results," Academic Radiol, 15:1526-33, 2008.
  • Insana MF, Wickline SA, "Multimodality biomolecular imaging," , Proc IEEE, vol 96, pp 378-81, 2008.
  • Tsou JK, Gower RM, Ting HJ, Schaff UY, Insana MF, Passerini AG, Simon SI, "Spatial regulation of inflammation by human aortic endothelial cells in a linear gradient of shear stress," Microcirculation 15:311-23, 2008.
  • Tsou JK, Simon SI, Barakat AI, Insana MF, "Role of ultrasonic shear rate estimation errors in assessing inflammatory response and vascular risk," Ultrasound Med Biol, 34: 963-972, 2008.

Articles in Conference Proceedings

  • Insana MF, "Statistical ultrasonics: the influence of Robert F. Wagner," Proc SPIE Medical Imaging: Image Perception, Observer Performance, and Technology Assessment, 7263:(in press), 2009.

Post-doctoral Associates and Visiting Scientists

  • Kathleen Toohey

Professional Societies

  • Biomedical Engineering Society, 2008 -

Service on Department Committees

  • Interim Department Head, Bioengineering (2008- )